"Sunlight destroys the COVID-19 virus quickly," reads the briefing.
Preliminary results from government lab experiments show that the coronavirus does not survive long in high temperatures and high humidity, and is quickly destroyed by sunlight, providing evidence from controlled tests of what scientists believed - but had not yet proved - to be true.
Vitamin D is important: It gets T cells going
SCIENTIFIC AMERICAN March 7, 2010 Vitamin D deficiency has been linked to a rapidly expanding inventory of ailments - including heart disease, cancer and the common cold. A new discovery demonstrates how the vitamin plays a major role in keeping the body healthy in the first place, by allowing the immune system's T cells to start doing their jobs.
For T cells to become active members of the body's immune system, they must transition from so-called "naive" T cells into either killer cells or helper cells (which are charged with "remembering" specific invaders). And, if ample vitamin D is not around, the T cells do not make that crucial transition, a group of researchers led by Carsten Geisler, head of the Department of International Health, Immunology and Microbiology at the University of Copenhagen, found.
They draw this conclusion based on their experiments with isolated naive human T cells. "When a T cell is exposed to a foreign pathogen, it extends a signaling device of 'antenna' known as a vitamin D receptor, with which it searches for vitamin D," Geisler said in a prepared statement. If there is an inadequate vitamin D level, he noted, "they won't even begin to mobilize."
Although this vitamin requirement might seem like a handicap to the immune system, the researchers proposed that the additional step involving the vitamin D receptor might serve an important evolutionary function: keeping T cells from ravaging healthy tissue. "Given that T cells are capable of explosive proliferation, the lag phase imposed by the vitamin D [receptor step] may diminish the risk of unwanted immunopathology," they noted in the study, which was published online March 7 in Nature Immunology.
The body naturally makes vitamin D when the skin is exposed to sunshine (it can also come from eggs and some fish products), but most people in the U.S. are considered deficient in the vitamin. A 2009 Archives of Internal Medicine study found that 77 per cent of U.S. adults and teenagers surveyed did not have the estimated minimum healthful level of 30 nanograms per milliliter in their blood. And just three per cent of blacks in the survey were getting enough of the vitamin, the 2009 report found.
Where to get Vitamin D
A 100-gram serving of wild salmon contains about 988 IU of vitamin D per serving, while farmed salmon contains 250 IU, on average. That's 124% and 32% of the DV, respectively.
Fresh Atlantic herring provides 216 IU per 100 gram, 27% of the DV. Pickled herring is also a good source of vitamin D, providing 112 IU per 100-gram serving, or 14% of the DV.
Canned sardines are a good source of vitamin D as well - one can 100 grams, contains 177 IU, or 22% of the DV.
Halibut and mackerel provide 384 IU and 360 IU per half a fillet, respectively.
Canned light tuna packs up to 268 IU of vitamin D in a 100-gram serving, which is 34% of the DV. It's also a good source of niacin and vitamin K. Unfortunately, canned tuna contains methylmercury, a toxin found in many types of fish. If it builds up in your body, it can cause serious health problems.
Eggs from commercially raised hens contain only about 37 IU of vitamin D per yolk or 5% of the suggested daily intake. However, eggs from hens raised outside or fed vitamin-D-enriched feed contain much higher levels.
Mushrooms can synthesize vitamin D2 when exposed to UV light. Only wild mushrooms or mushrooms treated with UV light are good sources of vitamin D.
Foods such as cow's milk, soy milk, orange juice, cereals, and oatmeal are sometimes fortified with vitamin D. These contain 54-136 IU per serving.
Cod liver oil contains 448 IU of vitamin D per teaspoon or 56% of the DV. It is also high in other nutrients, such as vitamin A and omega-3 fatty acids.
Reports on the success where Vitamin D reduces Covid-19 infection
There is growing non-scientific literature that Vitamin D and Zinc inhibit the CO-19 virus. Taking them should do no harm except to your pocket, and in a sea of bewilderment, they could be effective. We obtain vitamin D either through our diet, with certain foods such as oily fish and egg yolks being good sources, or through our exposure to ultraviolet B radiation from the sun.
Low levels of vitamin D found in some COVID patients.
Objective Studies have demonstrated a potential link between low vitamin D levels and an increased risk of infection with SARS-CoV-2 and poorer clinical outcomes but have not established temporality. This retrospective study examined if, and to what degree, a relationship exists between pre-infection serum vitamin D levels and disease severity and mortality of SARS-CoV-19.
Conclusions Among hospitalized COVID-19 patients, pre-infection deficiency of vitamin D was associated with increased disease severity and mortality. This new study conducted by the Azrieli Faculty of Medicine of Bar-Ilan University and its affiliate Galilee Medical Centre is among the first to show that pre-infection deficiency of 25-hydroxyvitamin D3 is associated with increased COVID-19 severity and mortality. 4 June 2021.
Professor Roger Seheult, MD explains the important role Vitamin D may have in the prevention and treatment of COVID-19. Dr. Seheult illustrates how Vitamin D works, summarizes the best available data and clinical trials on vitamin D, and discusses vitamin D dosage recommendations.
Good levels of vitamin D, the so-called sunshine vitamin, help people fight the coronavirus more quickly and effectively and reduce hospitalisation chances, Israeli researchers have concluded. 27 July 2020
Her team studied a 7,807-strong sample of Israelis who were tested for the coronavirus. It found that the average vitamin D level for people who screened negative was in the internationally-accepted "adequate" range, over 21 nanograms per milliliter, while the average for those who tested positive fell in the "inadequate" category under 19 nanograms per milliliter.
She argued that authorities must factor vitamin D needs into future restrictions, and avoid closing public outdoor spaces, like nature reserves and beaches, as happened during lockdowns.
Evidence recommends that vitamin D might be a crucial supportive agent for the immune system, mainly in cytokine response regulation against COVID-19.
This study found that most of the COVID-19 patients were suffering from vitamin D deficiency/insufficiency. Also, there is about a three times higher chance of getting infected with SARS-CoV-2 among vitamin D deficient individuals and about five times higher probability of developing the severe disease in vitamin D deficient patients. Vitamin D deficiency showed no significant association with mortality rates in this population.
This pilot study demonstrated that administration of a high dose of Calcifediol or 25-hydroxyvitamin D, a main metabolite of vitamin D endocrine system, significantly reduced the need for ICU treatment of patients requiring hospitalization due to proven COVID-19.
This studyfound that the mean serum 25-hydroxyvitamin D level was low in all COVID-19 patients, and most of them were suffering from vitamin D deficiency/insufficiency.
Don't Let COVID-19 Patients Die With Vitamin D Deficiency. January 5, 2021. In Surgeon General Luther Terry's 1964 Report on Smoking and Health ground breaking publication, saved tens of millions of lives from lung cancer, was based on a causation analysis by an advisory committee. MedPage Op-Ed: - We can't wait for perfect evidence!
The argument that vitamin D deficiency may contribute to more severe cases of Covid is gaining ground. It is now reaching the point where it is surprising that we are not hearing from leading medical officials and politicians that people should consider taking supplements to ensure they have sufficient vitamin D.
Very high intakes or 'mega supplements' will not help and may cause harm, and it is this that probably explains the authorities' reluctance to spread the message. Another factor may be the lack of lobbying. Vitamin supplements are cheap and unpatented, so big companies have no great incentive to push them. All the more reason for the government to do so.
Vitamin D reduces the risk of other acute respiratory infections. One interesting finding of this meta-analysis is that people who were very deficient (less than 25 nmol/L) saw the largest protective effect with an adjusted odd ratio of 0.58 and a 95% CI of 0.40 to 0.82. These are the same populations which seem to be at risk for severe Covid-19
Calcitriol, the active form of Vitamin D is active against the SARS-COV2 virus
Patients treated with calcifediol are less likely to be admitted to the ICU than controls
Several studies have now observed lower vitamin D levels among severe Covid-19 patients
Vitamin D is very low risk an adverse events of vitamin D supplementation can be easily managed by clinicians
It's important to note that the sun's UVB rays cannot penetrate through windows. So people who work next to sunny windows are still prone to vitamin D deficiency.
Both UVA (320-400 nm) and UVB (290 to 320 nm) are above the 200 nm drop and are not highly absorbed by water. Sunburn is thus still a concern underwater, at least in pure water.
Single Dose Vitamin D Flops in Moderate-Severe COVID
Randomized trial in Brazil disappoints February 18, 2021. Overall, 240 patients were randomized: 120 to a single oral dose of 200,000 IU of vitamin D and 120 to placebo. They were given the intervention after a mean of 10.3 days from symptom onset. The study did not address outpatients with mild COVID-19 or the use of vitamin D as prophylaxis against the disease.
Among Spanish hospitalized patients with severe COVID-19, a single dose of 200,000 IU of vitamin D3 supplementation was safe and increased 25-hydroxyvitamin D levels, but did not reduce hospital length of stay or any other clinically relevant outcomes vs placebo. The patients were given a dose of vitamin D3 after a relatively long time from symptom onset to randomization (ie, mean of 10.3 days). Further studies should determine whether preventive or early vitamin D3 supplementation could be useful in treating patients with COVID-19, especially those with mild or moderate disease.
No evidence that vitamin D is able to prevent or affect the severity of COVID-19 in individuals with European ancestry. Methods: We used two-sample Mendelian randomisation (MR) to assess the causal effect of vitamin D levels on SARS-CoV-2 infection risk and COVID-19 severity using publicly available data. We also carried out a genome-wide association analysis (GWA) of vitamin D deficiency in the UK Biobank (UKB). We used these results and two-sample MR to assess the causal effect of vitamin D deficiency on SARS-CoV-2 infection risk and COVID-19 severity.
Sun, fresh air & virus in 1920
In 1918 putting infected patients out in the sun helped because it inactivated the influenza virus.
It also kills bacteria that cause lung and other infections in hospitals.
During the First World War, military surgeons routinely used sunlight to heal infected wounds. They just knew it was a disinfectant.
What they didn't know was how it worked was that the placing patients outside in the sun was they could synthesise vitamin D in their skin if sunlight was strong enough.
There is considerable literature to support Vitamins success in reducing the effects of the SARS-CoV-2 virus
Vitamin B12, vitamin A, zinc and magnesium
The medical records analysis also found protective effects in patients taking vitamin A, vitamin B12, magnesium and zinc.
From the American Journal of Medical publication Zinc Lozenges and Zinc Sulfate Zinc is a known inhibitor of coronavirus replication. Clinical trials of zinc lozenges in the common cold have demonstrated modest reductions in the duration and severity of symptoms. By extension, this readily available nontoxic therapy could be deployed at the first signs of COVID-19. Zinc lozenges can be administered five times a day for up to 5 days and extended if needed if symptoms persist. The amount of elemental zinc lozenges is <25% of that in a single 220-mg zinc sulfate daily tablet. This dose of zinc sulfate has been effectively used in combination with antimalarials (HCQ)in the early treatment of high-risk outpatients with COVID-19.
What is the best dose of zinc for Covid-19 prevention?
Failed Vitamin Supplements
Supplements Fail for COVID-19 MedPage Today February 12, 2021
High-dose zinc and vitamin C (ascorbic acid) had no impact on the course of symptoms in patients with mild COVID-19, a randomized trial found.
There was no difference in the number of days to reach it whether patients received zinc gluconate, ascorbic acid, both supplements, or neither, reported Milind Desai, MD, of the Cleveland Clinic, and colleagues. In addition, there was no difference in secondary endpoints, including days to symptom resolution, the severity of symptoms, hospitalizations, or deaths, the authors wrote in JAMA Network Open.
Limitations to the data included no placebo group, and the trial was open-label, and stratification of symptoms by age, sex, race, or duration of symptoms prior to testing was not taken into account during the analysis. Some potential confounders, such as vitamin D levels, were also not examined.
Comments include, "Why was the study called A to Z when it only looked at two nutrients?
What about vitamin D, quercetin, resveratrol, green tea extract, glutathione, melatonin, and others with known anti-viral activity, many of which work synergistically? Check out FLCCC I-MASK+ protocol". "It seems to me that it would be more reasonable to test Vit C and zinc in dosages and administration routes that are commonly suggested by alt.practitioners." "Vit C, usually as sodium ascorbate via i.v. administration at dosages of 50 to 100 grams/day (yes grams). Zinc is claimed to have far greater anti-viral activity when combined with an ionophore such as quercitin or EGCG". "Vit C, usually as sodium ascorbate via i.v. administration at dosages of 50 to 100 grams/day (yes grams). Zinc is claimed to have far greater anti-viral activity when combined with an ionophore such as quercitin or EGCG. In addition, zinc with the ionophore should be taken every 2-4 hours, not once at bedtime".
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